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Abstract

Tetrahedron Letters 44 (2003) 4761–4763

Efficient one-pot synthesis of anti HIV and antitumor
compounds: harman and substituted harmans

Radhika S. Kusurkar,* Shailesh K. Goswami and Sandhya M. Vyas
Department of Chemistry, University of Pune, Pune 411 007 India
Received 16 January 2003; revised 7 April 2003; accepted 17 April 2003

Abstract—Anti HIV and antitumor compounds, harman and substituted harmans have been synthesized using electrocyclization
reactions as key steps. A one-pot reaction sequence was used to furnish these compounds in good overall yield. © 2003 Elsevier
Science Ltd. All rights reserved.


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